Thanks SS for the link.
Here are my
bios (F8) settings as they stand now. Orthos has been running for over 8 hours at 4.005Ghz with no problems. The temps are correct as this is a watercooled case.
MB Intelligent Tweaker (MIT)
Robust Graphics Booster:Auto
CPU Clock Ratio:9X
CPU Host Clock Control:Enabled
CPU Host Frequency(Mhz) :445
PCI Express Frequency (Mhz) :100
C.I.A.2

isabled
Performance Enhance :Standard
System Memory Multiplier (SPD)2.04B
Memory Frequency(Mhz):800 / 1068
DRAM Timing Selectable :Manual
Standard Timing Control
CAS Latency Time: :5
DRAM RAS# to CAS# :5
DRAM RAS# Precharge :5
Precharge Delay(tRAS) :15
Advanced Timing Control
ACT to ACT Delay(tRRD) :Auto
Rank Write to READ Delay :Auto
Write To Precharge Delay :Auto
Refresh to ACT Delay : Auto
Read To Precharge Delay : Auto
tRD :Auto
tRD Phase Adjustment :Auto
Command to #CS Timing: :Auto
Clock Driving and Skew Control
CPU/PCIEX Clock Driving Control :800mV
CPU Clock Skew Control : Normal
(G)
MCH Clock Skew Control : Normal
System Voltage ControlManual
DDR2 OverVoltage Control :+0.30
PCI-E OverVoltage Control :Normal
FSB OverVoltage Control :+0.15
(G)
MCH OverVoltage Control :+0.25
MCH Reference Voltage Control : Normal
DDR Reference Voltage Control : Normal
DDR Termination Voltage Control : Normal
CPU GTLREF1 Voltage* :Auto
CPU GTLREF2 Voltage* :Normal
CPU Voltage Control :1.325
Normal CPU Vcore :1.225
Advanced Bios Features
CPU Multi-Threading
Limit CPUID Max to 3: Disabled
No-Execute Memory Protect: Enabled
CPU Enhanced Halt(CIE)

isabled
CPU Thermal Monitor 2:Enabled
CPU EIST Function

isabled
Virtuaalization Technology:Enabled
Note: * Items are Hidden press [CTRL] + [F1] from the
bios main menu to access.